Abstract :More than 1.5 million people in the United States are diagnosed with sepsis every year, with
approximately 250,000 people dying of sepsis [1]. The annual incidence of sepsis is on the rise
[2]. Septic shock has even higher mortality rate, which is described as a state of decreased organ
perfusion leading to irreversible end organ damage [3]. The distributive or vasodilatory shock is the
most common type of shock which is characterized by the hypotension and peripheral vasodilation
despite patient having an optimal cardiac output [4,5].